Pupillometric Assessment of Excessive Daytime Sleepiness in Narcolepsy-Cataplexy
نویسندگان
چکیده
منابع مشابه
Pupillometric Assessment of Sleepiness in Narcolepsy
PURPOSE Excessive daytime sleepiness is highly prevalent in the general population, is the hallmark of narcolepsy, and is linked to significant morbidity. Clinical assessment of sleepiness remains challenging and the common objective multiple sleep latency test (MSLT) and subjective Epworth sleepiness scale (ESS) methods correlate poorly. We examined the relative utility of pupillary unrest ind...
متن کاملNarcolepsy with Cataplexy Is Characterized by Excessive Daytime Sleepiness, Cataplexy (a Sudden Bilateral Loss of Voluntary Muscle
NARCOLEPSY WITH CATAPLEXY IS CHARACTERIZED BY EXCESSIVE DAYTIME SLEEPINESS, CATAPLEXY (A SUDDEN BILATERAL LOSS OF VOLUNTARY MUSCLE tone provoked by emotions) and, facultatively, by other rapid eye movement (REM) sleep phenomena such as sleep paralysis and hallucinations (narcoleptic tetrad). Patients with narcolepsy with cataplexy have normal amounts of sleep over 24 hours, 1-3 but their day-ni...
متن کاملAssessment and management of excessive daytime sleepiness.
The obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is much the commonest ‘medical’ cause of sleepiness (Table 1), occurring in 1–4% of the middle-aged. OSAHS is the combination of sleepiness or two other major symptoms, such as unrefreshing sleep, difficulty concentrating and nocturnal choking, with five or more apnoeas plus hypopnoeas per hour slept (‘apnoea’ is defined as a 10-sec pause ...
متن کاملNarcolepsy: neural mechanisms of sleepiness and cataplexy.
Introduction Narcolepsy is a common cause of chronic sleepiness and is often accompanied by symptoms that include odd mixtures of sleep and wakefulness. A patient of ours is an intelligent and highly motivated young woman who developed unrelenting sleepiness during law school. No matter how much she slept at night, she struggled to stay awake while studying and her grades began to slip. One nig...
متن کاملScheduled naps in the management of daytime sleepiness in narcolepsy-cataplexy.
A repeated testing paradigm was used to assess the efficacy for the management of daytime sleepiness in narcolepsy-cataplexy of single long, multiple short and no-nap sleep/wake schedule conditions, with total sleep per 24 hours held constant. Eight narcoleptic subjects participated and followed each experimental schedule for two consecutive days, the second of which served as a test day during...
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ژورنال
عنوان ژورنال: Sleep
سال: 1991
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleep/14.2.121